Medico-Legal Update

Tariq Hafdhi Al-Khayat ¹, Rawaa Muayad Al-Quzweny ²

Affiliations
1 Professor, Clinical Bio Chemistry, College of Pharmacy, Al-Farahidi University, Baghdad, IQ
2 Asst. Lecturer, Clinical Bio Chemistry, College of Pharmacy, Al-Farahidi University, Baghdad, IQ

Abstract

The level of enzymes Alkaline phosphatase (ALP) and transaminase (AST &ALT) were measured in 99 Iraqi pregnant women from different areas in Baghdad city and compared with a control group comprising non-pregnant women (29women). Those pregnant women were classified into three groups according to the semester of pregnancy. (Group I to III ). New inclusion and exclusion criteria were applied in this study to increase the specificity. The result revealed a significant increase in the corresponding enzymes (p<0.001) for each simester of pregnancy when compared with the control group(non pregnant women). There were no significant changes in enzymes activity between group 1 (first trimester) and group II(second trimester) . The significant changes in ALP were observed between group 1 (first trimester) and group III (third trimester) p<0.001.The same trend was observed between group II (second trimester) and group III (third trimester). The result also revealed insignificant changes in AST/ALT ratio among all the groups including control group (p&#62). Conclusion: This study indicate the importance of the establishment of new reference values for the above mentioned enzyme during pregnancy and unsuitability of ALP in liver function test during pregnancy.

Keywords

Alkalinephosphatase, Transaminases Levels, Different Trimesters, Pregnancy Iraqi Women.

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